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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCDC2B All Species: 10.3
Human Site: S219 Identified Species: 28.33
UniProt: A2VCK2 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2VCK2 NP_001092904.1 349 37665 S219 E L L V P S P S L P R G C W Q
Chimpanzee Pan troglodytes XP_513279 346 37250 S216 E L L V P S P S L P R G C W Q
Rhesus Macaque Macaca mulatta XP_001100219 476 52674 T229 E L I F D K S T M R R P F G Q
Dog Lupus familis XP_854671 309 33936 C182 N P S L P R G C W H P P D P K
Cat Felis silvestris
Mouse Mus musculus Q5DU00 475 51934 A229 E L L F D K S A M R R P Y G Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510300 479 52805 T227 E L L F D K S T T R R P F G Q
Chicken Gallus gallus XP_001234164 215 24278 K88 Y V A A G F E K F K R L D Y L
Frog Xenopus laevis NP_001079645 486 54297 S235 D L I F S K A S I R R A H G S
Zebra Danio Brachydanio rerio NP_001032778 448 50578 N248 H S D S T L L N S P E R E G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 28.7 49.8 N.A. 29.6 N.A. N.A. 29.6 35.5 29.4 33.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 44.3 57.8 N.A. 42.3 N.A. N.A. 42.1 44.4 44.2 45.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 6.6 N.A. 33.3 N.A. N.A. 33.3 6.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 46.6 20 N.A. 46.6 N.A. N.A. 40 20 40 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 12 0 0 12 12 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 23 0 0 % C
% Asp: 12 0 12 0 34 0 0 0 0 0 0 0 23 0 0 % D
% Glu: 56 0 0 0 0 0 12 0 0 0 12 0 12 0 0 % E
% Phe: 0 0 0 45 0 12 0 0 12 0 0 0 23 0 0 % F
% Gly: 0 0 0 0 12 0 12 0 0 0 0 23 0 56 0 % G
% His: 12 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % H
% Ile: 0 0 23 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 45 0 12 0 12 0 0 0 0 12 % K
% Leu: 0 67 45 12 0 12 12 0 23 0 0 12 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 34 0 23 0 0 34 12 45 0 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 % Q
% Arg: 0 0 0 0 0 12 0 0 0 45 78 12 0 0 12 % R
% Ser: 0 12 12 12 12 23 34 34 12 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 12 0 0 23 12 0 0 0 0 0 0 % T
% Val: 0 12 0 23 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 23 0 % W
% Tyr: 12 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _